COVID-19 in a patient with a flare of systemic lupus erythematosus: A rare case-report

Abdulrahman Alharthy, Fahad Faqihi, Nasir Nasim, Alfateh Noor, Saima Akhtar, Ahmed Balshi, Abdullah Balhamar, Saleh A. Alqahtani, Ziad A. Memish, Dimitrios Karakitsos

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


This is a rare case-report of a young female with systemic lupus erythematosus and end-stage kidney disease (on maintenance hemodialysis) who was admitted to our intensive care unit due to life-threatening COVID-19. The patient was diagnosed with a flare of lupus; while being on maintenance hydroxychloroquine therapy. However, after the administration of steroids she made an uneventful recovery and was discharged home. In this report, the diagnostic dilemmas and the therapeutic challenges due to the overlapping clinical, imaging, and laboratory findings between lupus and COVID-19 pneumonitis are outlined. In conclusion, patients with lupus may be affected by COVID-19 despite the administration of hydroxychloroquine. The administration of steroids may have a beneficial effect on mitigating both the flare of SLE and the COVID-19 associated hyperinflammation.

Original languageEnglish (US)
Article number101252
JournalRespiratory Medicine Case Reports
StatePublished - Jan 2020


  • Acute respiratory failure
  • COVID-19
  • End-stage kidney disease
  • Hydroxychloroquine
  • Steroid therapy
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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