Counting single molecules in sub-nanolitre droplets

T. D. Rane; C. M. Puleo; K. J. Liu; Y. Zhang; A. P. Lee; T. H. Wang

doi:10.1039/b917503b

Counting single molecules in sub-nanolitre droplets

T. D. Rane
, C. M. Puleo
, K. J. Liu
, Y. Zhang
, A. P. Lee
, T. H. Wang

Whiting School of Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.

Original language	English (US)
Pages (from-to)	161-164
Number of pages	4
Journal	Lab on a Chip
Volume	10
Issue number	2
DOIs	https://doi.org/10.1039/b917503b
State	Published - 2010

ASJC Scopus subject areas

Bioengineering
Biochemistry
General Chemistry
Biomedical Engineering

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10.1039/b917503b

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title = "Counting single molecules in sub-nanolitre droplets",

abstract = "We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.",

author = "Rane, \{T. D.\} and Puleo, \{C. M.\} and Liu, \{K. J.\} and Y. Zhang and Lee, \{A. P.\} and Wang, \{T. H.\}",

year = "2010",

doi = "10.1039/b917503b",

language = "English (US)",

volume = "10",

pages = "161--164",

journal = "Lab on a Chip",

issn = "1473-0197",

publisher = "Royal Society of Chemistry",

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T1 - Counting single molecules in sub-nanolitre droplets

AU - Rane, T. D.

AU - Puleo, C. M.

AU - Liu, K. J.

AU - Zhang, Y.

AU - Lee, A. P.

AU - Wang, T. H.

PY - 2010

Y1 - 2010

N2 - We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.

AB - We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.

UR - https://www.scopus.com/pages/publications/73149118681

UR - https://www.scopus.com/pages/publications/73149118681#tab=citedBy

U2 - 10.1039/b917503b

DO - 10.1039/b917503b

M3 - Article

AN - SCOPUS:73149118681

SN - 1473-0197

VL - 10

SP - 161

EP - 164

JO - Lab on a Chip

JF - Lab on a Chip

IS - 2

ER -

Counting single molecules in sub-nanolitre droplets

Abstract

ASJC Scopus subject areas

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