Coordination of peroxide to the Cu_M center of peptidylglycine α-hydroxylating monooxygenase (PHM): Structural and computational study

Medicine & Life Sciences

• peptidylglycine monooxygenase 100%
• Peroxides 71%
• Copper 34%
• Hydroxylation 26%
• Hydrogen Peroxide 22%
• Density Functional Theory 19%
• Ligands 16%
• Reducing Agents 14%
• Neuropeptides 11%
• Glycine 11%
• Catalytic Domain 10%
• Electrons 9%
• Oxygen 8%
• Hormones 8%
• Peptides 7%
• Proteins 4%

Chemical Compounds

• Peptidylglycine 94%
• Peroxide 50%
• Monooxygenase Reaction 15%
• Hydroperoxide 9%
• Hormone 9%
• Coordination Sphere 9%
• Glycine 8%
• Ligand 8%
• Hydrogen Peroxide 7%
• Bioactivity 6%
• Density Functional Theory 5%
• Environment 5%
• Electron Particle 5%
• Dioxygen 4%
• Energy 4%
• Protein 3%