Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease

David Bonekamp; Heather Jacene; Detlef Bartelt; Nafi Aygun

doi:10.1097/RLU.0b013e31818c4e9c

Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease

David Bonekamp, Heather Jacene, Detlef Bartelt, Nafi Aygun

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Fibrous dysplasia (FD) accounts for 7% of benign bone tumors. It is a developmental disorder of unclear etiology. The lamellar cancellous bone of the medullary cavity is replaced with immature fibroosseous tissue. We describe a case of FD of the skull in a patient of advanced age (69 years) with recent diagnosis of colon cancer, which changed its FDG activity and CT appearance within 10 months of follow-up. Surgical biopsy confirmed FD. Several case reports describe FDG-avid FD, but conversion of metabolic activity late in life is probably unusual.

Original language	English (US)
Pages (from-to)	909-911
Number of pages	3
Journal	Clinical nuclear medicine
Volume	33
Issue number	12
DOIs	https://doi.org/10.1097/RLU.0b013e31818c4e9c
State	Published - Dec 2008
Externally published	Yes

Keywords

Conversion
FDG PET
FDG positive
Fibrous dysplasia
Lytic bone lesion
Skull

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RLU.0b013e31818c4e9c

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title = "Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease",

abstract = "Fibrous dysplasia (FD) accounts for 7% of benign bone tumors. It is a developmental disorder of unclear etiology. The lamellar cancellous bone of the medullary cavity is replaced with immature fibroosseous tissue. We describe a case of FD of the skull in a patient of advanced age (69 years) with recent diagnosis of colon cancer, which changed its FDG activity and CT appearance within 10 months of follow-up. Surgical biopsy confirmed FD. Several case reports describe FDG-avid FD, but conversion of metabolic activity late in life is probably unusual.",

keywords = "Conversion, FDG PET, FDG positive, Fibrous dysplasia, Lytic bone lesion, Skull",

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AU - Bonekamp, David

AU - Jacene, Heather

AU - Bartelt, Detlef

AU - Aygun, Nafi

PY - 2008/12

Y1 - 2008/12

N2 - Fibrous dysplasia (FD) accounts for 7% of benign bone tumors. It is a developmental disorder of unclear etiology. The lamellar cancellous bone of the medullary cavity is replaced with immature fibroosseous tissue. We describe a case of FD of the skull in a patient of advanced age (69 years) with recent diagnosis of colon cancer, which changed its FDG activity and CT appearance within 10 months of follow-up. Surgical biopsy confirmed FD. Several case reports describe FDG-avid FD, but conversion of metabolic activity late in life is probably unusual.

AB - Fibrous dysplasia (FD) accounts for 7% of benign bone tumors. It is a developmental disorder of unclear etiology. The lamellar cancellous bone of the medullary cavity is replaced with immature fibroosseous tissue. We describe a case of FD of the skull in a patient of advanced age (69 years) with recent diagnosis of colon cancer, which changed its FDG activity and CT appearance within 10 months of follow-up. Surgical biopsy confirmed FD. Several case reports describe FDG-avid FD, but conversion of metabolic activity late in life is probably unusual.

KW - Conversion

KW - FDG PET

KW - FDG positive

KW - Fibrous dysplasia

KW - Lytic bone lesion

KW - Skull

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Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease

Abstract

Keywords

ASJC Scopus subject areas

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