Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

Dharmpal S. Dodd; Alan P. Kozikowski

doi:10.1016/S0040-4039(00)79943-6

Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

Dharmpal S. Dodd, Alan P. Kozikowski

School of Medicine

Research output: Contribution to journal › Article › peer-review

103 Scopus citations

Abstract

An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.

Original language	English (US)
Pages (from-to)	977-980
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	7
DOIs	https://doi.org/10.1016/S0040-4039(00)79943-6
State	Published - Feb 14 1994

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)79943-6

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@article{dc417d78cfbb431ba979da0170209044,

title = "Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol",

abstract = "An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.",

author = "Dodd, {Dharmpal S.} and Kozikowski, {Alan P.}",

note = "Funding Information: Acknowledgement: We are indebted to the Mayo Foundation for support of this research.",

year = "1994",

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doi = "10.1016/S0040-4039(00)79943-6",

language = "English (US)",

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journal = "Tetrahedron Letters",

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T1 - Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

AU - Dodd, Dharmpal S.

AU - Kozikowski, Alan P.

N1 - Funding Information: Acknowledgement: We are indebted to the Mayo Foundation for support of this research.

PY - 1994/2/14

Y1 - 1994/2/14

N2 - An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.

AB - An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.

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U2 - 10.1016/S0040-4039(00)79943-6

DO - 10.1016/S0040-4039(00)79943-6

M3 - Article

AN - SCOPUS:0028297004

SN - 0040-4039

VL - 35

SP - 977

EP - 980

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

Abstract

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