Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T A Nguyen; Jeffrey W. Shupp; Lauren T. Moffatt; Jessica C. Ramella-Roman

doi:10.1117/12.2039661

Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T A Nguyen, Jeffrey W. Shupp, Lauren T. Moffatt, Jessica C. Ramella-Roman

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

Original language	English (US)
Title of host publication	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Publisher	SPIE
Volume	8945
ISBN (Print)	9780819498588
DOIs	https://doi.org/10.1117/12.2039661
State	Published - 2014
Externally published	Yes
Event	Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI - San Francisco, CA, United States Duration: Feb 1 2014 → Feb 2 2014

Other

Other	Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI
Country/Territory	United States
City	San Francisco, CA
Period	2/1/14 → 2/2/14

Keywords

Digimouse
Electrical Shock
Thermal imaging

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2039661

Cite this

Nguyen, TTA, Shupp, JW, Moffatt, LT & Ramella-Roman, JC 2014, Construction of a digital and physical mouse model aimed at the study of electrical shock. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8945, 894508, SPIE, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI, San Francisco, CA, United States, 2/1/14. https://doi.org/10.1117/12.2039661

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Y1 - 2014

N2 - Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

AB - Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

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KW - Thermal imaging

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Construction of a digital and physical mouse model aimed at the study of electrical shock

Abstract

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Keywords

ASJC Scopus subject areas

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