Constitutive phosphodiesterase activity restricts spontaneous beating rate of cardiac pacemaker cells by suppressing local Ca2+ releases

Tatiana M. Vinogradova, Syevda Sirenko, Alexey E. Lyashkov, Antoine Younes, Yue Li, Weizhong Zhu, Dongmei Yang, Abdul M. Ruknudin, Harold Spurgeon, Edward G. Lakatta

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Biochemistry, Genetics and Molecular Biology