@article{fe891c4bf1674e0b810623d9dfe00bfd,
title = "Consortium Building for Nurse Scientists Interested in Symptoms Research in the Era of Precision Health",
abstract = "Purpose: This article aims to provide perspectives on the establishment of a consortium for nurse scientists with similar career trajectories interested in cancer-related symptoms (CRS) research. Hereby, we describe the development of and recent outcomes from the CRS consortium, the lessons learned in establishing the consortium, and future directions to advance the science of CRS. Model and Methods: New and innovative strategies are needed to address the complexity of CRS research. A CRS consortium was created to allow a mechanism for oncology nurse scientists with varying expertise to collaborate to advance CRS research. The National Institutes of Health (NIH) Symptom Science Model (SSM) guides the research of the CRS Consortium. Discussion and Conclusions: A need for improved CRS assessment and management has been identified. The CRS consortium was created as a collaborative think tank to begin to address this need. Guided by the NIH SSM, CRS consortium members have worked to define symptom phenotypes, enhance understanding of the biologic mechanisms that can contribute to symptom phenotypes, and develop tailored interventions to improve symptom management. Dissemination of the CRS consortium efforts involve publications and presentations. Clinical Implications: Nurse scientists interested in symptom science and biobehavorial research face many challenges on how to initiate and sustain independent programs of research. Through the formation of a CRS consortium, oncology nurse scientists can work together to address identified issues in symptom measurement and management.",
keywords = "Cancer-related symptoms, consortium, symptom science",
author = "Hsiao, {Chao Pin} and Kristin Dickinson and Velda Gonzalez-Mercado and Kelly, {Debra Lynch} and Nada Lukkahatai and Margaret McCabe and Samantha Mayo and Rita Musanti and Saligan, {Leorey N.}",
note = "Funding Information: The goals of the CRS consortium are to provide peer mentoring, promote collaboration, and improve the development of early‐ and mid‐career research programs focused on CRS. The CRS consortium currently has nine members, oncology nurse scientists from academic medical centers across North America, who engage in a collective governance structure where all consortium members share the same values and responsibilities in advancing the interest of the consortium. Decisions such as acceptance of new members are made by consensus. There is no financial obligation to become a consortium member, and participation in any of the consortium projects is purely voluntary. Each consortium member can propose specific projects and set meetings. In the past 2 years, the CRS consortium has contributed to nursing research and science through (a) publication of state‐of‐the‐science review papers, (b) hosting a symposium during the CANS, (c) developing a common data file of measures to standardize collection of study outcomes to be used in CRS research, and (d) engaging in mentorship and scholarly collaborations. Peer mentorship in the CRS consortium is carried out through preliminary discussion and review of grant applications and through collaborative projects aimed to generate initial data to be used for grant applications. These strategies seem to be effective because consortium members have successfully received funding through several NIH training grant mechanisms ( https://www.ninr.nih.gov/sites/files/docs/gdmr-faq.pdf ), such as the K99/R00 grant (Pathway to Independence Award) to explore expression of genes related to three cellular stress response pathways (apoptosis, autophagy, and necrosis) in cancer‐related fatigue (CRF), a K01 grant (Mentored Research Scientist Development Award) to test a mitochondrial bioenergetic mechanism of radiation‐induced fatigue in patients with prostate cancer undergoing radiation therapy, and an F32 grant (Ruth L. Kirschstein National Research Service Award) to explore the biologic/gut microbial processes related to the relationship of chemo‐radiotherapy, dysbiosis, and fatigue in the rectal cancer population. In addition, foundational grants (e.g., Oncology Nursing Society Foundation [ONS], International Society of Nurses in Genetics [ISONG]) also provided opportunities for CRS consortium members to build initial data to support future grant applications. Publisher Copyright: {\textcopyright} 2019 Sigma Theta Tau International",
year = "2020",
month = mar,
day = "1",
doi = "10.1111/jnu.12534",
language = "English (US)",
volume = "52",
pages = "183--191",
journal = "Journal of Nursing Scholarship",
issn = "1527-6546",
publisher = "Wiley-Blackwell",
number = "2",
}