TY - JOUR
T1 - Consensus expert recommendations for referral of Parkinson’s disease patients for deep brain stimulation surgery
AU - Functional Neurosurgical working group of the Parkinson Study Group
AU - Safarpour, Delaram
AU - Spindler, Meredith
AU - Turner, Travis H.
AU - Patel, Neepa
AU - Vaou, Okeanis
AU - Cabrera, Laura Y.
AU - Tolleson, Christopher
AU - Tipton, Philip W.
AU - Aquino, Camila
AU - Herrington, Todd M.
AU - Sidiropoulos, Christos
AU - Hantke, Nathan
AU - Lotia, Mitesh
AU - Miocinovic, Svjetlana
AU - Sharma, Vibhash D.
AU - Mills, Kelly A.
AU - Wyman-Chick, Kathryn
AU - Kilbane, Camilla
AU - Luca, Corneliu
AU - Almeida, Leonardo
AU - Rosenow, Joshua
AU - Ooi, Hwai Yin
AU - Mari, Zoltan
AU - Luo, Lan
AU - Munhoz, Renato P.
AU - Jesus, Sol De
AU - Sarva, Harini
AU - Arena, Monica
AU - Revuelta, Gonzalo
AU - Chou, Kelvin L.
AU - Fasano, Alfonso
AU - Siddiqui, Mustafa S.
AU - Jimenez-Shahed, Joohi
AU - Fasano, Alfonso
AU - De Jesus, Sol
AU - Munhoz, Renato P.
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2026/12
Y1 - 2026/12
N2 - Deep brain Stimulation (DBS) surgery effectively alleviates troublesome motor symptoms of Parkinson’s disease (PD) such as tremor, rigidity, bradykinesia, motor fluctuations and dyskinesia. It also improves some non-motor symptoms and quality of life. DBS should thus be considered when these symptoms interfere with quality of life despite optimal medical treatment. While DBS benefits are clear, access by eligible patients remains low. Patients and their caregivers should be educated regarding DBS surgery and referrals for surgical evaluation should occur alongside ongoing medication adjustments—particularly when those changes fail to adequately control motor symptoms—regardless of the stage of disease progression. This international panel of DBS experts developed consensus recommendations with the goals of promoting timely referrals and approvals, while reducing misconceptions and stigma associated with brain surgery. These recommendations provide a framework for referring providers, ensuring that appropriate candidates receive timely access to this beneficial treatment.
AB - Deep brain Stimulation (DBS) surgery effectively alleviates troublesome motor symptoms of Parkinson’s disease (PD) such as tremor, rigidity, bradykinesia, motor fluctuations and dyskinesia. It also improves some non-motor symptoms and quality of life. DBS should thus be considered when these symptoms interfere with quality of life despite optimal medical treatment. While DBS benefits are clear, access by eligible patients remains low. Patients and their caregivers should be educated regarding DBS surgery and referrals for surgical evaluation should occur alongside ongoing medication adjustments—particularly when those changes fail to adequately control motor symptoms—regardless of the stage of disease progression. This international panel of DBS experts developed consensus recommendations with the goals of promoting timely referrals and approvals, while reducing misconceptions and stigma associated with brain surgery. These recommendations provide a framework for referring providers, ensuring that appropriate candidates receive timely access to this beneficial treatment.
UR - https://www.scopus.com/pages/publications/105028771557
UR - https://www.scopus.com/pages/publications/105028771557#tab=citedBy
U2 - 10.1038/s41531-025-01241-3
DO - 10.1038/s41531-025-01241-3
M3 - Review article
C2 - 41484162
AN - SCOPUS:105028771557
SN - 2373-8057
VL - 12
JO - npj Parkinson's Disease
JF - npj Parkinson's Disease
IS - 1
M1 - 30
ER -