Congenital malformations associated with the administration of oral anticoagulants during pregnancy

Paul S. Lietman; J. M. Pettifor; R. Benson

doi:10.1016/S0022-3476(75)80986-3

Congenital malformations associated with the administration of oral anticoagulants during pregnancy

Paul S. Lietman, J. M. Pettifor, R. Benson

School of Medicine

Research output: Contribution to journal › Article › peer-review

143 Scopus citations

Abstract

Three small infants whose mothers had received oral anticoagulant therapy during the first trimester of pregnancy are described. These infants all had hypoplasia of the nasal bones, and two had stippling of epiphyses and bones and deformities of the bones of the hand. One child is mentally retarded. It is suggested that these abnormalities may be related to maternal oral anticoagulant therapy during the first trimester.

Original language	English (US)
Pages (from-to)	459-462
Number of pages	4
Journal	The Journal of pediatrics
Volume	86
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3476(75)80986-3
State	Published - Mar 1975

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(75)80986-3

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title = "Congenital malformations associated with the administration of oral anticoagulants during pregnancy",

abstract = "Three small infants whose mothers had received oral anticoagulant therapy during the first trimester of pregnancy are described. These infants all had hypoplasia of the nasal bones, and two had stippling of epiphyses and bones and deformities of the bones of the hand. One child is mentally retarded. It is suggested that these abnormalities may be related to maternal oral anticoagulant therapy during the first trimester.",

author = "Lietman, {Paul S.} and Pettifor, {J. M.} and R. Benson",

year = "1975",

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doi = "10.1016/S0022-3476(75)80986-3",

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AU - Lietman, Paul S.

AU - Pettifor, J. M.

AU - Benson, R.

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Y1 - 1975/3

N2 - Three small infants whose mothers had received oral anticoagulant therapy during the first trimester of pregnancy are described. These infants all had hypoplasia of the nasal bones, and two had stippling of epiphyses and bones and deformities of the bones of the hand. One child is mentally retarded. It is suggested that these abnormalities may be related to maternal oral anticoagulant therapy during the first trimester.

AB - Three small infants whose mothers had received oral anticoagulant therapy during the first trimester of pregnancy are described. These infants all had hypoplasia of the nasal bones, and two had stippling of epiphyses and bones and deformities of the bones of the hand. One child is mentally retarded. It is suggested that these abnormalities may be related to maternal oral anticoagulant therapy during the first trimester.

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ER -

Congenital malformations associated with the administration of oral anticoagulants during pregnancy

Abstract

ASJC Scopus subject areas

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