Congenital agenesis of right parotid gland confounds MIBG scan interpretation in craniocervical neuroblastoma.

Don Udall; Steve Y. Cho

doi:10.1097/rlu.0b013e318219b2b9

Congenital agenesis of right parotid gland confounds MIBG scan interpretation in craniocervical neuroblastoma.

Don Udall, Steve Y. Cho

School of Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 10-month-old boy with left infraorbital temporal neuroblastoma presented for I-123 metaiodobenzylguanidine scan with SPECT/CT for staging. Symmetrical metaiodobenzylguanidine uptake in salivary glands is usually considered normal. In this case of right parotid agenesis, symmetrical uptake was misleading. Tumor in the right mandibular ramus masqueraded as normal parotid gland. Repeat imaging 3 months after chemotherapy revealed absence of physiologic right parotid gland activity. Correlation with CT from SPECT/CT demonstrated right parotid agenesis, confirmed on MRI. Few cases of unilateral parotid agenesis are reported in published literature. We also discuss the potential added value of higher-quality CT images in SPECT/CT tumor imaging.

Original language	English (US)
Pages (from-to)	e162-164
Journal	Clinical nuclear medicine
Volume	36
Issue number	11
DOIs	https://doi.org/10.1097/rlu.0b013e318219b2b9
State	Published - Nov 2011

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/rlu.0b013e318219b2b9

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title = "Congenital agenesis of right parotid gland confounds MIBG scan interpretation in craniocervical neuroblastoma.",

abstract = "A 10-month-old boy with left infraorbital temporal neuroblastoma presented for I-123 metaiodobenzylguanidine scan with SPECT/CT for staging. Symmetrical metaiodobenzylguanidine uptake in salivary glands is usually considered normal. In this case of right parotid agenesis, symmetrical uptake was misleading. Tumor in the right mandibular ramus masqueraded as normal parotid gland. Repeat imaging 3 months after chemotherapy revealed absence of physiologic right parotid gland activity. Correlation with CT from SPECT/CT demonstrated right parotid agenesis, confirmed on MRI. Few cases of unilateral parotid agenesis are reported in published literature. We also discuss the potential added value of higher-quality CT images in SPECT/CT tumor imaging.",

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N2 - A 10-month-old boy with left infraorbital temporal neuroblastoma presented for I-123 metaiodobenzylguanidine scan with SPECT/CT for staging. Symmetrical metaiodobenzylguanidine uptake in salivary glands is usually considered normal. In this case of right parotid agenesis, symmetrical uptake was misleading. Tumor in the right mandibular ramus masqueraded as normal parotid gland. Repeat imaging 3 months after chemotherapy revealed absence of physiologic right parotid gland activity. Correlation with CT from SPECT/CT demonstrated right parotid agenesis, confirmed on MRI. Few cases of unilateral parotid agenesis are reported in published literature. We also discuss the potential added value of higher-quality CT images in SPECT/CT tumor imaging.

AB - A 10-month-old boy with left infraorbital temporal neuroblastoma presented for I-123 metaiodobenzylguanidine scan with SPECT/CT for staging. Symmetrical metaiodobenzylguanidine uptake in salivary glands is usually considered normal. In this case of right parotid agenesis, symmetrical uptake was misleading. Tumor in the right mandibular ramus masqueraded as normal parotid gland. Repeat imaging 3 months after chemotherapy revealed absence of physiologic right parotid gland activity. Correlation with CT from SPECT/CT demonstrated right parotid agenesis, confirmed on MRI. Few cases of unilateral parotid agenesis are reported in published literature. We also discuss the potential added value of higher-quality CT images in SPECT/CT tumor imaging.

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Congenital agenesis of right parotid gland confounds MIBG scan interpretation in craniocervical neuroblastoma.

Abstract

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