Abstract
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV-based therapeutics at the preclinical and clinical levels. This review outlines topic-specific action items that, if addressed, will enhance the development of bestpractice models for EV therapies.
Original language | English (US) |
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Pages (from-to) | 1730-1739 |
Number of pages | 10 |
Journal | Stem Cells Translational Medicine |
Volume | 6 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2017 |
Keywords
- Cellular therapy
- Clinical translation
- Clinical trials
- Exosomes
- Extracellular vesicles
- Microvesicles
- Stem cells
- Therapeutics
ASJC Scopus subject areas
- General Medicine