Concepts in nuclear replacement

Ann N. Sieber, John P. Kostuik

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


This article describes the pathogenesis of early nuclear failure and current philosophical approaches to artificial, biological, and bioartificial nucleus replacement. Necessary in this review is an overview of current approaches to nucleus replacement with prosthetics and various gel materials.

Original languageEnglish (US)
Pages (from-to)S322-S324
JournalSpine Journal
Issue number6 SUPPL.
StatePublished - 2004


  • Nucleus pulposus
  • Polymer
  • Prosthesis

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology


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