Computer simulations of cardiac defibrillation: A look inside the heart

Natalia Trayanova, James Eason, Felipe Aguel

Research output: Contribution to journalArticlepeer-review


This paper presents for the first time computer simulations of electrical defibrillation in the heart in a realistic model of cardiac structure and membrane ionic processes. The content of the paper focuses primarily on model development. Two models of defibrillation are presented here: a three-dimensional slice of the canine heart that encompasses both ventricular cavities, and a full rabbit heart model. The two sets of simulations employing the described models demonstrate transmural electrical activity in the heart during and after the shock that has not yet been observed experimentally due to present limitations in recording procedures. The models developed here are intended for exploration of the mechanisms for defibrillation as well as to address issues pertinent to the clinical procedure of defibrillation such as electrode location and shock waveform.

Original languageEnglish (US)
Pages (from-to)259-270
Number of pages12
JournalComputing and Visualization in Science
Issue number4
StatePublished - Jul 2002
Externally publishedYes

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Software
  • Modeling and Simulation
  • General Engineering
  • Computer Vision and Pattern Recognition
  • Computational Theory and Mathematics


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