Computer-Assisted Analysis of Regulation of the Glycerol-3-Phosphate Metabolism in Genomes of Proteobacteria

L. V. Danilova; M. S. Gelfand; V. A. Lyubetsky; O. N. Laikova

doi:10.1023/A:1026037027266

Computer-Assisted Analysis of Regulation of the Glycerol-3-Phosphate Metabolism in Genomes of Proteobacteria

L. V. Danilova, M. S. Gelfand, V. A. Lyubetsky, O. N. Laikova

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Comparative computer-assisted analysis was used to study putative G1pR regulons responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of α-, β-, and γ-proteobacteria. New palindromic G1pR-binding signals were identified in γ-proteobacteria, consensus sequences being TGTTCGATAACGAACA for Enterobacteriaceae, wTTTTCGTATACGAAAAw for Pseudomonadaceae, and AATGCTCGATCGAGCATT for Vibrionaceae. The signals in α- and β-proteobacteria were also identified: they contained 3-4 direct TTTCGTT repeats separated by 3-4 nucleotide pairs.

Original language	English (US)
Pages (from-to)	716-722
Number of pages	7
Journal	Molecular Biology
Volume	37
Issue number	5
DOIs	https://doi.org/10.1023/A:1026037027266
State	Published - 2003
Externally published	Yes

Keywords

Computer-assisted analysis
G1pR
Operon structure
Tandem repeats
α-proteobacteria
β-proteobacteria
γ-proteobacteria

ASJC Scopus subject areas

Biophysics
Structural Biology

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10.1023/A:1026037027266

Cite this

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title = "Computer-Assisted Analysis of Regulation of the Glycerol-3-Phosphate Metabolism in Genomes of Proteobacteria",

abstract = "Comparative computer-assisted analysis was used to study putative G1pR regulons responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of α-, β-, and γ-proteobacteria. New palindromic G1pR-binding signals were identified in γ-proteobacteria, consensus sequences being TGTTCGATAACGAACA for Enterobacteriaceae, wTTTTCGTATACGAAAAw for Pseudomonadaceae, and AATGCTCGATCGAGCATT for Vibrionaceae. The signals in α- and β-proteobacteria were also identified: they contained 3-4 direct TTTCGTT repeats separated by 3-4 nucleotide pairs.",

keywords = "Computer-assisted analysis, G1pR, Operon structure, Tandem repeats, α-proteobacteria, β-proteobacteria, γ-proteobacteria",

author = "Danilova, {L. V.} and Gelfand, {M. S.} and Lyubetsky, {V. A.} and Laikova, {O. N.}",

note = "Funding Information: This work was supported by the Howard Hughes Medical Institute (grant 55000309).",

year = "2003",

doi = "10.1023/A:1026037027266",

language = "English (US)",

volume = "37",

pages = "716--722",

journal = "Molecular Biology",

issn = "0026-8933",

publisher = "Maik Nauka-Interperiodica Publishing",

number = "5",

}

TY - JOUR

T1 - Computer-Assisted Analysis of Regulation of the Glycerol-3-Phosphate Metabolism in Genomes of Proteobacteria

AU - Danilova, L. V.

AU - Gelfand, M. S.

AU - Lyubetsky, V. A.

AU - Laikova, O. N.

N1 - Funding Information: This work was supported by the Howard Hughes Medical Institute (grant 55000309).

PY - 2003

Y1 - 2003

N2 - Comparative computer-assisted analysis was used to study putative G1pR regulons responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of α-, β-, and γ-proteobacteria. New palindromic G1pR-binding signals were identified in γ-proteobacteria, consensus sequences being TGTTCGATAACGAACA for Enterobacteriaceae, wTTTTCGTATACGAAAAw for Pseudomonadaceae, and AATGCTCGATCGAGCATT for Vibrionaceae. The signals in α- and β-proteobacteria were also identified: they contained 3-4 direct TTTCGTT repeats separated by 3-4 nucleotide pairs.

AB - Comparative computer-assisted analysis was used to study putative G1pR regulons responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of α-, β-, and γ-proteobacteria. New palindromic G1pR-binding signals were identified in γ-proteobacteria, consensus sequences being TGTTCGATAACGAACA for Enterobacteriaceae, wTTTTCGTATACGAAAAw for Pseudomonadaceae, and AATGCTCGATCGAGCATT for Vibrionaceae. The signals in α- and β-proteobacteria were also identified: they contained 3-4 direct TTTCGTT repeats separated by 3-4 nucleotide pairs.

KW - Computer-assisted analysis

KW - G1pR

KW - Operon structure

KW - Tandem repeats

KW - α-proteobacteria

KW - β-proteobacteria

KW - γ-proteobacteria

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DO - 10.1023/A:1026037027266

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JO - Molecular Biology

JF - Molecular Biology

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ER -

Computer-Assisted Analysis of Regulation of the Glycerol-3-Phosphate Metabolism in Genomes of Proteobacteria

Abstract

Keywords

ASJC Scopus subject areas

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