Complications of nasal SARS-CoV-2 testing: a review

James H. Clark; Sharon Pang; Robert M. Naclerio; Matthew Kashima

doi:10.1136/jim-2021-001962

Complications of nasal SARS-CoV-2 testing: a review

James H. Clark, Sharon Pang, Robert M. Naclerio, Matthew Kashima

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs.

Original language	English (US)
Pages (from-to)	1399-1403
Number of pages	5
Journal	Journal of Investigative Medicine
Volume	69
Issue number	8
DOIs	https://doi.org/10.1136/jim-2021-001962
State	Published - Dec 1 2021

Keywords

COVID-19
education
medical
nasal cavity

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1136/jim-2021-001962

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title = "Complications of nasal SARS-CoV-2 testing: a review",

abstract = "Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs.",

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AU - Clark, James H.

AU - Pang, Sharon

AU - Naclerio, Robert M.

AU - Kashima, Matthew

N1 - Publisher Copyright: © American Federation for Medical Research 2021.

PY - 2021/12/1

Y1 - 2021/12/1

N2 - Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs.

AB - Transnasal swab testing for the detection of SARS-CoV-2 is well established. The Centers for Disease Control and Prevention advocates swabbing either of the anterior nares, middle turbinate, or nasopharynx for specimen collection depending on available local resources. The purpose of this review is to investigate complications related to transnasal SARS-CoV-2 testing with specific attention to specimen collection site and swab approach. The literature demonstrates that while nasopharyngeal swabbing is associated with an increased risk of complications, it should remain the gold-standard test due to greater diagnostic accuracy relative to anterior nasal and middle turbinate swabs.

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Complications of nasal SARS-CoV-2 testing: a review

Abstract

Keywords

ASJC Scopus subject areas

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