Compensating control participants when the intervention is of significant value: Experience in Guatemala, India, Peru and Rwanda

Ashlinn K. Quinn, Kendra Williams, Lisa M. Thompson, Ghislaine Rosa, Anaité Díaz-Artiga, Gurusamy Thangavel, Kalpana Balakrishnan, J. Jaime Miranda, Joshua P. Rosenthal, Thomas F. Clasen, Steven A. Harvey

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The Household Air Pollution Intervention Network (HAPIN) trial is a randomised controlled trial in Guatemala, India, Peru and Rwanda to assess the health impact of a clean cooking intervention in households using solid biomass for cooking. The HAPIN intervention-a liquefied petroleum gas (LPG) stove and 18-month supply of LPG-has significant value in these communities, irrespective of potential health benefits. For control households, it was necessary to develop a compensation strategy that would be comparable across four settings and would address concerns about differential loss to follow-up, fairness and potential effects on household economics. Each site developed slightly different, contextually appropriate compensation packages by combining a set of uniform principles with local community input. In Guatemala, control compensation consists of coupons equivalent to the LPG stove's value that can be redeemed for the participant's choice of household items, which could include an LPG stove. In Peru, control households receive several small items during the trial, plus the intervention stove and 1 month of fuel at the trial's conclusion. Rwandan participants are given small items during the trial and a choice of a solar kit, LPG stove and four fuel refills, or cash equivalent at the end. India is the only setting in which control participants receive the intervention (LPG stove and 18 months of fuel) at the trial's end while also being compensated for their time during the trial, in accordance with local ethics committee requirements. The approaches presented here could inform compensation strategy development in future multi-country trials.

Original languageEnglish (US)
Article numbere001567
JournalBMJ Global Health
Issue number4
StatePublished - Aug 1 2019


  • compensation
  • ethics
  • multi-country trial
  • randomised controlled trial

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health


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