Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi

Yigal S. Gur; Troy H. Farncombe; P. Hendrik Pretorius; Howard C. Gifford; Manoj V. Narayanan; Eric C. Frey; Daniel Gagnon; Michael A. King

doi:10.1109/NSSMIC.2001.1009257

Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi

Yigal S. Gur, Troy H. Farncombe, P. Hendrik Pretorius, Howard C. Gifford, Manoj V. Narayanan, Eric C. Frey, Daniel Gagnon, Michael A. King

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Scatter can be a confounding problem in the detection of perfusion defects in cardiac perfusion imaging. The goal of this investigation was to compare practical methods of scatter compensation representing different classes of compensation strategies. The methods investigated were: 1) modification of the energy window; 2) use of effective as values of attenuation coefficients; 3) estimating the scatter distribution from energy spectrum information; and 4) estimating the scatter distribution in the spatial domain using the attenuation maps and scatter kernels. Monte Carlo simulated projections from two MCAT source distributions were used to investigate the impact of the various methods on residual scatter and cardiac uniformity. The investigation showed that each of the methods reduce the scatter significantly; however, the spatial domain method gave the least variation with the different source distributions and the best uniformity.

Original language	English (US)
Pages (from-to)	2188-2192
Number of pages	5
Journal	IEEE Nuclear Science Symposium and Medical Imaging Conference
Volume	4
DOIs	https://doi.org/10.1109/NSSMIC.2001.1009257
State	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2001.1009257

Cite this

@article{8ddb7fcccc9a4ffb9aa2c0bd301a5c3c,

title = "Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi",

abstract = "Scatter can be a confounding problem in the detection of perfusion defects in cardiac perfusion imaging. The goal of this investigation was to compare practical methods of scatter compensation representing different classes of compensation strategies. The methods investigated were: 1) modification of the energy window; 2) use of effective as values of attenuation coefficients; 3) estimating the scatter distribution from energy spectrum information; and 4) estimating the scatter distribution in the spatial domain using the attenuation maps and scatter kernels. Monte Carlo simulated projections from two MCAT source distributions were used to investigate the impact of the various methods on residual scatter and cardiac uniformity. The investigation showed that each of the methods reduce the scatter significantly; however, the spatial domain method gave the least variation with the different source distributions and the best uniformity.",

author = "Gur, {Yigal S.} and Farncombe, {Troy H.} and Pretorius, {P. Hendrik} and Gifford, {Howard C.} and Narayanan, {Manoj V.} and Frey, {Eric C.} and Daniel Gagnon and King, {Michael A.}",

year = "2002",

doi = "10.1109/NSSMIC.2001.1009257",

language = "English (US)",

volume = "4",

pages = "2188--2192",

journal = "IEEE Nuclear Science Symposium and Medical Imaging Conference",

issn = "1095-7863",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi

AU - Gur, Yigal S.

AU - Farncombe, Troy H.

AU - Pretorius, P. Hendrik

AU - Gifford, Howard C.

AU - Narayanan, Manoj V.

AU - Frey, Eric C.

AU - Gagnon, Daniel

AU - King, Michael A.

PY - 2002

Y1 - 2002

N2 - Scatter can be a confounding problem in the detection of perfusion defects in cardiac perfusion imaging. The goal of this investigation was to compare practical methods of scatter compensation representing different classes of compensation strategies. The methods investigated were: 1) modification of the energy window; 2) use of effective as values of attenuation coefficients; 3) estimating the scatter distribution from energy spectrum information; and 4) estimating the scatter distribution in the spatial domain using the attenuation maps and scatter kernels. Monte Carlo simulated projections from two MCAT source distributions were used to investigate the impact of the various methods on residual scatter and cardiac uniformity. The investigation showed that each of the methods reduce the scatter significantly; however, the spatial domain method gave the least variation with the different source distributions and the best uniformity.

AB - Scatter can be a confounding problem in the detection of perfusion defects in cardiac perfusion imaging. The goal of this investigation was to compare practical methods of scatter compensation representing different classes of compensation strategies. The methods investigated were: 1) modification of the energy window; 2) use of effective as values of attenuation coefficients; 3) estimating the scatter distribution from energy spectrum information; and 4) estimating the scatter distribution in the spatial domain using the attenuation maps and scatter kernels. Monte Carlo simulated projections from two MCAT source distributions were used to investigate the impact of the various methods on residual scatter and cardiac uniformity. The investigation showed that each of the methods reduce the scatter significantly; however, the spatial domain method gave the least variation with the different source distributions and the best uniformity.

UR - http://www.scopus.com/inward/record.url?scp=0035554236&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035554236&partnerID=8YFLogxK

U2 - 10.1109/NSSMIC.2001.1009257

DO - 10.1109/NSSMIC.2001.1009257

M3 - Article

AN - SCOPUS:0035554236

SN - 1095-7863

VL - 4

SP - 2188

EP - 2192

JO - IEEE Nuclear Science Symposium and Medical Imaging Conference

JF - IEEE Nuclear Science Symposium and Medical Imaging Conference

ER -

Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this