Abstract
This study compared results given by the channelized Hotelling observer (CHO) with rotationally symmetric (RS) channels and the CHO with rotationally oriented (RO) channels for a myocardial SPECT defect detection study using simulated SPECT images. The 4D NCAT phantom was used to model a patient population with variations in anatomy, defects (size, location and contrast) and 99mTc-sestmaibi uptake in the organs. Low noise, parallel projection data were generated using Monte Carlo simulation. Poisson noise was added to generate noisy realizations. Data were reconstructed using OS-EM at 1 & 4 subsets/iteration and at 1, 3, 5, 7 & 9 iterations and were then converted to 2D short-axis images. The CHO-RS used 3 RS frequency channels and the CHO-RO used 12 channels (3 frequency channels at 4 orientations) to form image vectors. For each OS-EM parameter setting, the detectability index was estimated from 864 defect-present & 864 defect-absent vectors. The CHO-RS and CHO-RO models predicted the same optimum OS-EM parameter setting of 4 subsets/iteration and 5 iterations and gave nearly the same ranking of all the parameter settings. The CHO-RO gave high absolute detectability values. In conclusion, for defect detection in simulated myocardial SPECT images, the CHO-RO model does not offer an advantage over the CHO-RS model.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3620-3623 |
| Number of pages | 4 |
| Journal | IEEE Nuclear Science Symposium Conference Record |
| Volume | 6 |
| State | Published - Dec 1 2004 |
| Event | 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy Duration: Oct 16 2004 → Oct 22 2004 |
ASJC Scopus subject areas
- Radiation
- Nuclear and High Energy Physics
- Radiology Nuclear Medicine and imaging