Comparison of oxygenation measurements in pediatric patients during sickle cell crises

J. A. Craft; E. Alessandrini; L. B. Kenney; B. Klein; G. Bray; N. L.C. Luban; R. Meek; V. M. Nadkarni

doi:10.1016/S0022-3476(94)70260-8

Comparison of oxygenation measurements in pediatric patients during sickle cell crises

J. A. Craft, E. Alessandrini, L. B. Kenney, B. Klein, G. Bray, N. L.C. Luban, R. Meek, V. M. Nadkarni

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Measurements of the saturation of arterial blood with oxygen (Sao₂) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that Sao₂ measured by pulse oximetry overestimated cooximeter-measured Sao₂ (mean bias, 6.9%; p < 0.001). The blood gas machine–calculated Sao₂ also overestimated cooximeter-measured Sao₂ (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F. (J PEDIATR 1994;124:93-5)

Original language	English (US)
Pages (from-to)	93-95
Number of pages	3
Journal	Journal of Pediatrics
Volume	124
Issue number	1
DOIs	https://doi.org/10.1016/S0022-3476(94)70260-8
State	Published - 1994
Externally published	Yes

Keywords

CI
COHb
Carboxyhemoglobin
Confidence interval
Fetal hemoglobin
HbF
HbS
MetHb
Methemoglobin
SaO
Saturation of arterial blood with oxygen
Saturation of arterial blood with oxygen, measured by pulse oximetry
Sickle hemoglobin
SpO

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1016/S0022-3476(94)70260-8

Cite this

@article{438cb9e5c0d442aa80a479bbfb1ff30d,

title = "Comparison of oxygenation measurements in pediatric patients during sickle cell crises",

abstract = "Measurements of the saturation of arterial blood with oxygen (Sao2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that Sao2 measured by pulse oximetry overestimated cooximeter-measured Sao2 (mean bias, 6.9%; p < 0.001). The blood gas machine–calculated Sao2 also overestimated cooximeter-measured Sao2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F. (J PEDIATR 1994;124:93-5)",

keywords = "CI, COHb, Carboxyhemoglobin, Confidence interval, Fetal hemoglobin, HbF, HbS, MetHb, Methemoglobin, SaO, Saturation of arterial blood with oxygen, Saturation of arterial blood with oxygen, measured by pulse oximetry, Sickle hemoglobin, SpO",

author = "Craft, {J. A.} and E. Alessandrini and Kenney, {L. B.} and B. Klein and G. Bray and Luban, {N. L.C.} and R. Meek and Nadkarni, {V. M.}",

note = "Funding Information: Supported by a Research Grant from the Brandywine Professional Association. ",

year = "1994",

doi = "10.1016/S0022-3476(94)70260-8",

language = "English (US)",

volume = "124",

pages = "93--95",

journal = "Journal of Pediatrics",

issn = "0022-3476",

publisher = "Mosby Inc.",

number = "1",

}

TY - JOUR

T1 - Comparison of oxygenation measurements in pediatric patients during sickle cell crises

AU - Craft, J. A.

AU - Alessandrini, E.

AU - Kenney, L. B.

AU - Klein, B.

AU - Bray, G.

AU - Luban, N. L.C.

AU - Meek, R.

AU - Nadkarni, V. M.

N1 - Funding Information: Supported by a Research Grant from the Brandywine Professional Association.

PY - 1994

Y1 - 1994

N2 - Measurements of the saturation of arterial blood with oxygen (Sao2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that Sao2 measured by pulse oximetry overestimated cooximeter-measured Sao2 (mean bias, 6.9%; p < 0.001). The blood gas machine–calculated Sao2 also overestimated cooximeter-measured Sao2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F. (J PEDIATR 1994;124:93-5)

AB - Measurements of the saturation of arterial blood with oxygen (Sao2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that Sao2 measured by pulse oximetry overestimated cooximeter-measured Sao2 (mean bias, 6.9%; p < 0.001). The blood gas machine–calculated Sao2 also overestimated cooximeter-measured Sao2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F. (J PEDIATR 1994;124:93-5)

KW - CI

KW - COHb

KW - Carboxyhemoglobin

KW - Confidence interval

KW - Fetal hemoglobin

KW - HbF

KW - HbS

KW - MetHb

KW - Methemoglobin

KW - SaO

KW - Saturation of arterial blood with oxygen

KW - Saturation of arterial blood with oxygen, measured by pulse oximetry

KW - Sickle hemoglobin

KW - SpO

UR - http://www.scopus.com/inward/record.url?scp=0028058019&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028058019&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(94)70260-8

DO - 10.1016/S0022-3476(94)70260-8

M3 - Article

C2 - 8283382

AN - SCOPUS:0028058019

SN - 0022-3476

VL - 124

SP - 93

EP - 95

JO - Journal of Pediatrics

JF - Journal of Pediatrics

IS - 1

ER -

Comparison of oxygenation measurements in pediatric patients during sickle cell crises

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this