Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals

Joseph Yeboah; Robyn L. McClelland; Tamar S. Polonsky; Gregory L. Burke; Christopher T. Sibley; Daniel O'Leary; Jeffery J. Carr; David C. Goff; Philip Greenland; David M. Herrington

Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals

Joseph Yeboah
, Robyn L. McClelland
, Tamar S. Polonsky
, Gregory L. Burke
, Christopher T. Sibley
, Daniel O'Leary
, Jeffery J. Carr
, David C. Goff
, Philip Greenland
, David M. Herrington

Research output: Contribution to journal › Article › peer-review

Abstract

Context: Risk markers including coronary artery calcium, carotid intima-media thickness, ankle-brachial index, brachial flow-mediated dilation, high-sensitivity C-reactive protein (CRP), and family history of coronary heart disease (CHD) have been reported to improve on the Framingham Risk Score (FRS) for prediction of CHD, but there are no direct comparisons of these markers for risk prediction in a single cohort. Objective: We compared improvement in prediction of incident CHD/ cardiovascular disease (CVD) of these 6 risk markers within intermediate-risk participants (FRS >5%-

Original language	English (US)
Pages (from-to)	788-795
Number of pages	8
Journal	Journal of the American Medical Association
Volume	308
Issue number	8
State	Published - Aug 22 2012
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

@article{e3b811c0fae543f89746bc1ab9d0d98b,

title = "Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals",

abstract = "Context: Risk markers including coronary artery calcium, carotid intima-media thickness, ankle-brachial index, brachial flow-mediated dilation, high-sensitivity C-reactive protein (CRP), and family history of coronary heart disease (CHD) have been reported to improve on the Framingham Risk Score (FRS) for prediction of CHD, but there are no direct comparisons of these markers for risk prediction in a single cohort. Objective: We compared improvement in prediction of incident CHD/ cardiovascular disease (CVD) of these 6 risk markers within intermediate-risk participants (FRS >5\%-",

author = "Joseph Yeboah and McClelland, \{Robyn L.\} and Polonsky, \{Tamar S.\} and Burke, \{Gregory L.\} and Sibley, \{Christopher T.\} and Daniel O'Leary and Carr, \{Jeffery J.\} and Goff, \{David C.\} and Philip Greenland and Herrington, \{David M.\}",

year = "2012",

month = aug,

day = "22",

language = "English (US)",

volume = "308",

pages = "788--795",

journal = "Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "8",

}

TY - JOUR

T1 - Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals

AU - Yeboah, Joseph

AU - McClelland, Robyn L.

AU - Polonsky, Tamar S.

AU - Burke, Gregory L.

AU - Sibley, Christopher T.

AU - O'Leary, Daniel

AU - Carr, Jeffery J.

AU - Goff, David C.

AU - Greenland, Philip

AU - Herrington, David M.

PY - 2012/8/22

Y1 - 2012/8/22

N2 - Context: Risk markers including coronary artery calcium, carotid intima-media thickness, ankle-brachial index, brachial flow-mediated dilation, high-sensitivity C-reactive protein (CRP), and family history of coronary heart disease (CHD) have been reported to improve on the Framingham Risk Score (FRS) for prediction of CHD, but there are no direct comparisons of these markers for risk prediction in a single cohort. Objective: We compared improvement in prediction of incident CHD/ cardiovascular disease (CVD) of these 6 risk markers within intermediate-risk participants (FRS >5%-

AB - Context: Risk markers including coronary artery calcium, carotid intima-media thickness, ankle-brachial index, brachial flow-mediated dilation, high-sensitivity C-reactive protein (CRP), and family history of coronary heart disease (CHD) have been reported to improve on the Framingham Risk Score (FRS) for prediction of CHD, but there are no direct comparisons of these markers for risk prediction in a single cohort. Objective: We compared improvement in prediction of incident CHD/ cardiovascular disease (CVD) of these 6 risk markers within intermediate-risk participants (FRS >5%-

UR - https://www.scopus.com/pages/publications/84865320778

UR - https://www.scopus.com/pages/publications/84865320778#tab=citedBy

M3 - Article

C2 - 22910756

AN - SCOPUS:84865320778

SN - 0098-7484

VL - 308

SP - 788

EP - 795

JO - Journal of the American Medical Association

JF - Journal of the American Medical Association

IS - 8

ER -

Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this