TY - JOUR
T1 - Comparison of neuropsychological performance between AIDS-Free injecting drug users and homosexual men
AU - Concha, Mauricio
AU - Seines, Ola A.
AU - Vlahov, David
AU - Nance-Sproson, Tish
AU - Updike, Marcia
AU - Royal, Walter
AU - Palenicek, John
AU - Mc Arthur, Justin C.
PY - 1997
Y1 - 1997
N2 - We performed a cross-sectional comparison of the baseline neuropsychologic performance of 107 injecting drug users and 230 homosexual men participating in two longitudinal studies. Cognitive tests measured attention, memory and psychomotor speed. Using multiple regression modelling, the analysis adjusted for age, IQ score, race, six-month history of alcohol, cocaine, opiates and marijuana use, HIV serostatus and CD4+ lymphocyte count. Injecting drug users showed significantly poorer scores in all neuropsychologic tests in the univariate analysis. However, once adjusted for age, IQ score and race, only Rey Complex Figure tests were significantly worse among injecting drug users. These data indicate that age and IQ score rather than risk group account primarily for the differences in the cognitive performance, regardless of serostatus and CD4+ count.
AB - We performed a cross-sectional comparison of the baseline neuropsychologic performance of 107 injecting drug users and 230 homosexual men participating in two longitudinal studies. Cognitive tests measured attention, memory and psychomotor speed. Using multiple regression modelling, the analysis adjusted for age, IQ score, race, six-month history of alcohol, cocaine, opiates and marijuana use, HIV serostatus and CD4+ lymphocyte count. Injecting drug users showed significantly poorer scores in all neuropsychologic tests in the univariate analysis. However, once adjusted for age, IQ score and race, only Rey Complex Figure tests were significantly worse among injecting drug users. These data indicate that age and IQ score rather than risk group account primarily for the differences in the cognitive performance, regardless of serostatus and CD4+ count.
KW - Acquired immunodeficiency syndrome
KW - Cognition
KW - Homosexual men
KW - Human immunodeficiency virus
KW - Injecting drug users
KW - Neuropsychologic tests
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U2 - 10.1159/000109674
DO - 10.1159/000109674
M3 - Article
C2 - 9057169
AN - SCOPUS:0031056616
SN - 0251-5350
VL - 16
SP - 78
EP - 85
JO - Neuroepidemiology
JF - Neuroepidemiology
IS - 2
ER -