Comparison of hepatitis C virus testing recommendations in high-income countries

Risha Irvin, Kathleen Ward, Tracy Agee, Noele P. Nelson, Claudia Vellozzi, David L. Thomas, Alexander J. Millman

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


AIM To investigate hepatitis C virus (HCV) testing recommendations from the United States and other high-income countries. METHODS A comprehensive search for current HCV testing recommendations from the top quartile of United Nations Human Development Index (HDI) countries (very high HDI) was performed using Google and reviewed from May 1 - October 30, 2014 and re-reviewed April 1 - October 2, 2017. RESULTS Of the 51 countries identified, 16 had HCV testing recommendations from a government body or recommendations issued collaboratively between a government and a medical organization. Of these 16 countries, 15 had HCV testing recommendations that were primarily risk-based and highlight behaviors, exposures, and conditions that are associated with HCV transmission in that region. In addition to risk-based testing, the HCV Guidance Panel (United States) incorporates recommendations for a one-time test for individuals born during 1945-1965 (the birth cohort) without prior ascertainment of risk into their guidance. In addition to the United States, six other countries either have an age-based testing recommendation or recommend one-time testing for all adults independent of risk factors typical of the region. CONCLUSION This review affirmed the similarities of the HCV Guidance Panel's guidance with those of recommendations from very high HDI countries.

Original languageEnglish (US)
Pages (from-to)743-751
Number of pages9
JournalWorld Journal of Hepatology
Issue number10
StatePublished - Oct 1 2018


  • Guidelines
  • Hepatitis C
  • Mass screening
  • Recommendations
  • Testing

ASJC Scopus subject areas

  • Hepatology


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