Comparison of estrogen-induced hyperplasia to endometrial carcinoma

Belur S. Bhagavan, Tim H. Parmley, Neil B. Rosenshein, Joan L. Jefferys, Jeane Ann Grisso, Paul D. Stolley

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Use of exogenous estrogens has been associated with endometrial cancer in a number of case-control studies. This observed association could be biased as a result of frequent misclassification of estrogen-induced hyperplasia as endometrial cancer. To evaluate this possibility, pathology slides from 233 patients with a hospital diagnosis of endometrial cancer were reviewed independently by two pathologists. The hospital diagnosis was confirmed by both pathologists in 86% of the cases, indicating that the misclassification of hyperplasia as carcinoma is uncommon.

Original languageEnglish (US)
Pages (from-to)12-15
Number of pages4
JournalObstetrics and gynecology
Issue number1
StatePublished - Jul 1984

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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