Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats

Brian C. Cooley; Mark M. Jones; A. Lee Dellon

doi:10.1002/micr.1920040105

Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats

Brian C. Cooley, Mark M. Jones, A. Lee Dellon

School of Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.

Original language	English (US)
Pages (from-to)	1-4
Number of pages	4
Journal	Microsurgery
Volume	4
Issue number	1
DOIs	https://doi.org/10.1002/micr.1920040105
State	Published - 1983

ASJC Scopus subject areas

Surgery

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title = "Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats",

abstract = "A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.",

author = "Cooley, {Brian C.} and Jones, {Mark M.} and Dellon, {A. Lee}",

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AU - Jones, Mark M.

AU - Dellon, A. Lee

PY - 1983

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N2 - A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.

AB - A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.

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Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats

Abstract

ASJC Scopus subject areas

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