TY - JOUR
T1 - Comparison of demographic factors and cardiovascular risk factor control among U.S. adults with type 2 diabetes by insulin treatment classification
AU - Wong, Kalina
AU - Glovaci, Diana
AU - Malik, Shaista
AU - Franklin, Stanley S.
AU - Wygant, Gail
AU - Iloeje, Uchenna
AU - Kan, Hongjun
AU - Wong, Nathan D.
N1 - Funding Information:
This project was presented in part at the American Heart Association Scientific Sessions, Chicago, IL, November 2010. This project was supported by a contract from Bristol Myers-Squibb to the University of California, Irvine. Dr. Iloje and Ms. Wygant are employees of Bristol Myers-Squibb and Dr. Kan was formerly an employee of Bristol Myers-Squibb. Dr. Wong receives research funding from Bristol Myers-Squibb and Merck and is a consultant from Abbott Laboratories. Kalina Wong is of no relation to Dr. Nathan Wong.
PY - 2012/5
Y1 - 2012/5
N2 - Aims: Data on glucose and cardiovascular disease (CVD) risk factor control among persons with type 2 diabetes mellitus (DM) according to insulin treatment status are lacking. We examined DM control, risk factors, and comorbidities among U.S. persons according to insulin treatment status. Methods: In the U.S. National Health and Nutrition Examination Surveys 2003-2006, we examined in 10,637 adults aged ≥ 30 with type 2 DM the extent of control of A1c, LDL-C, HDL-C, triglycerides, and blood pressure (BP) and composite goal attainment by insulin use status. Results: 6.6% (n = 889, projected to 14.3 million) had type 2 DM; of these, 22.9% were insulin users and 57.2% were treated only by other diabetes medications. Overall, 58.2% had an A1c < 7% (53 mmol/mol) (insulin users 33.1%, non-insulin treated 66.1%, and 77.9% of those not on medication, p < 0.0001). Overall, 44.2% were at a BP goal of < 130/80 mmHg, 43.8% had an LDL-C < 100 mg/dl (2.6 mmol/L), and 13.9% a BMI < 25 kg/m 2. Only 10.2% were simultaneously at A1c, LDL, and BP goals (5.4% of those on insulin). Conclusions: U.S. adults with type 2 DM, especially those treated with insulin remain inadequately controlled for A1c and CVD risk factors and have a high prevalence of comorbidities.
AB - Aims: Data on glucose and cardiovascular disease (CVD) risk factor control among persons with type 2 diabetes mellitus (DM) according to insulin treatment status are lacking. We examined DM control, risk factors, and comorbidities among U.S. persons according to insulin treatment status. Methods: In the U.S. National Health and Nutrition Examination Surveys 2003-2006, we examined in 10,637 adults aged ≥ 30 with type 2 DM the extent of control of A1c, LDL-C, HDL-C, triglycerides, and blood pressure (BP) and composite goal attainment by insulin use status. Results: 6.6% (n = 889, projected to 14.3 million) had type 2 DM; of these, 22.9% were insulin users and 57.2% were treated only by other diabetes medications. Overall, 58.2% had an A1c < 7% (53 mmol/mol) (insulin users 33.1%, non-insulin treated 66.1%, and 77.9% of those not on medication, p < 0.0001). Overall, 44.2% were at a BP goal of < 130/80 mmHg, 43.8% had an LDL-C < 100 mg/dl (2.6 mmol/L), and 13.9% a BMI < 25 kg/m 2. Only 10.2% were simultaneously at A1c, LDL, and BP goals (5.4% of those on insulin). Conclusions: U.S. adults with type 2 DM, especially those treated with insulin remain inadequately controlled for A1c and CVD risk factors and have a high prevalence of comorbidities.
KW - Cardiovascular risk factors
KW - Control
KW - Diabetes mellitus
KW - Epidemiology
KW - Insulin
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U2 - 10.1016/j.jdiacomp.2012.03.006
DO - 10.1016/j.jdiacomp.2012.03.006
M3 - Article
C2 - 22502939
AN - SCOPUS:84861645197
SN - 1056-8727
VL - 26
SP - 169
EP - 174
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
IS - 3
ER -