Comparative Treatment Outcomes for Idiopathic Subglottic Stenosis: 5-Year Update

William S. Tierney, Li Ching Huang, Sheau Chiann Chen, Lynn D. Berry, Catherine Anderson, Milan R. Amin, Michael S. Benninger, Joel H. Blumin, Jonathan M. Bock, Paul C. Bryson, Paul F. Castellanos, Matthew S. Clary, Seth M. Cohen, Brianna K. Crawley, Seth H. Dailey, James J. Daniero, Alessandro de Alarcon, Donald T. Donovan, Eric S. Edell, Dale C. EkbomDaniel S. Fink, Ramon A. Franco, Catherine Gaelyn Garrett, Elizabeth A. Guardiani, Alexander T. Hillel, Henry T. Hoffman, Norman D. Hogikyan, Rebecca J. Howell, Michael M. Johns, Jan L. Kasperbauer, Sid M. Khosla, Cheryl Kinnard, Robbi A. Kupfer, Alexander J. Langerman, Robert J. Lentz, Robert R. Lorenz, David G. Lott, Samir S. Makani, Fabien Maldonado, Laura Matrka, Andrew J. McWhorter, Albert L. Merati, Matthew Mori, James L. Netterville, Karla O'Dell, Julina Ongkasuwan, Gregory N. Postma, Lindsay S. Reder, Sarah L. Rohde, Brent E. Richardson, Otis B. Rickman, Clark A. Rosen, Matthew Rohlfing, Michael J. Rutter, Guri S. Sandhu, Joshua S. Schindler, Glenn Todd Schneider, Rupali N. Shah, Andrew G. Sikora, Robert J. Sinard, Marshall E. Smith, Libby J. Smith, Ahmed M.S. Soliman, Sigríður Sveinsdóttir, David Veivers, Sunil P. Verma, Paul M. Weinberger, Philip A. Weissbrod, Christopher T. Wootten, Yu Shyr, David O. Francis, Alexander Gelbard

Research output: Contribution to journalArticlepeer-review


The North American Airway Collaborative (NoAAC) previously published a 3-year multi-institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating treatment effectiveness. Patients in the NoAAC cohort were re-enrolled for 2 additional years and followed using the prespecified published protocol. Consistent with prior data, prospective observation of 487 iSGS patients for 5 years showed treatment effectiveness differed by modality. Cricotracheal resection maintained the lowest rate of recurrent operation (5%), followed by endoscopic resection with adjuvant medical therapy (30%) and endoscopic dilation (50%). These data support the initial observations and continue to provide value to providers and patients navigating longitudinal decision-making. Level of evidence: 2—prospective cohort study.

Original languageEnglish (US)
Pages (from-to)1570-1575
Number of pages6
JournalOtolaryngology - Head and Neck Surgery (United States)
Issue number6
StatePublished - Jun 2023


  • cricotracheal
  • dilation
  • dyspnea
  • endoscopic resection
  • iSGS
  • idiopathic
  • laryngology
  • subglottic stenosis
  • tracheal resection

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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