Comparative quantification of contractile force of cardiac muscle using a micro-mechanical cell force measurement system

Seokchang Ryu, Byungkyu Kim, Deokho Kim, Sukho Park

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In order to develop the cell based robot, we presented a micro-mechanical force measurement system for the biological muscle actuators, which utilize glucose as a power source for potential application in digestive organ. The proposed system is composed of a micro-manipulator, a force transducer with a glass probe, a signal processor, an inverted microscope and video recoding system. Using this measurement system, the contractile force and frequency of the cardiac myocytes were measured in real time and the magnitudes of the contractile force of each cardiac myocyte under different conditions were compared. From the quantitative experimental results, we could estimate that the force of cardiac myocytes is about 20-40 μN, and show that there is difference between the control cells and the micro-patterned cells.

Original languageEnglish (US)
Title of host publicationProceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Pages5077-5080
Number of pages4
StatePublished - 2005
Externally publishedYes
Event2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China
Duration: Sep 1 2005Sep 4 2005

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume7 VOLS
ISSN (Print)0589-1019

Other

Other2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Country/TerritoryChina
CityShanghai
Period9/1/059/4/05

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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