Abstract
The in vitro activities of bacitracin and mupirocin were compared for seven different strains of methicillin-resistant Staphylococcus aureus. Six of seven strains showed bacitracin minimum inhibitory concentrations (MICs) of 0.5 to 1.0 units/mL, and all seven had mupirocin MICs of 0.5 to 2 μg/mL. Time-kill studies revealed 2.6- to 4.5-log reduction in 24 hours with strains susceptible to bacitracin (4 units/mL) and 0 to 2.2 reduction with mupirocin (16 μg/mL). Bacitracin should be considered further for in vivo studies because of enhanced bacteriocidal effect and lower cost (Infect Control Hosp Epidemiol 1996;17:178-180).
Original language | English (US) |
---|---|
Pages (from-to) | 178-180 |
Number of pages | 3 |
Journal | Infection control and hospital epidemiology |
Volume | 17 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1996 |
ASJC Scopus subject areas
- Epidemiology
- Microbiology (medical)
- Infectious Diseases