Comparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosus

J. Karsh; R. P. Kimberly; N. I. Stahl; P. H. Plotz; J. L. Decker

doi:10.1002/art.1780231215

Comparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosus

J. Karsh, R. P. Kimberly, N. I. Stahl, P. H. Plotz, J. L. Decker

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Uncontrolled observations have suggested that ibuprofen may be host beneficial in the control of joint and chest pain. In addition, the larger experience with this drug in other arthritides has implied that changes in hepatic and renal function are rarely encountered. We undertook, therefore, a randomized trial to establish and compare the relative efficacies and toxicities of ibuprofen and aspirin in patients with systemic lupus erythematosus.

Original language	English (US)
Pages (from-to)	1401-1404
Number of pages	4
Journal	Arthritis and Rheumatism
Volume	23
Issue number	12
DOIs	https://doi.org/10.1002/art.1780231215
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Immunology
Rheumatology

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abstract = "Uncontrolled observations have suggested that ibuprofen may be host beneficial in the control of joint and chest pain. In addition, the larger experience with this drug in other arthritides has implied that changes in hepatic and renal function are rarely encountered. We undertook, therefore, a randomized trial to establish and compare the relative efficacies and toxicities of ibuprofen and aspirin in patients with systemic lupus erythematosus.",

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AB - Uncontrolled observations have suggested that ibuprofen may be host beneficial in the control of joint and chest pain. In addition, the larger experience with this drug in other arthritides has implied that changes in hepatic and renal function are rarely encountered. We undertook, therefore, a randomized trial to establish and compare the relative efficacies and toxicities of ibuprofen and aspirin in patients with systemic lupus erythematosus.

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Comparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosus

Abstract

ASJC Scopus subject areas

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