TY - JOUR
T1 - Comparative effectiveness research in lung diseases and sleep disorders
T2 - Recommendations from the National Heart, Lung, and Blood Institute Workshop
AU - Lieu, Tracy A.
AU - Au, David
AU - Krishnan, Jerry A.
AU - Moss, Marc
AU - Selker, Harry
AU - Harabin, Andrea
AU - Taggart, Virginia
AU - Connors, Alfred
AU - Apter, Andrea
AU - Blaisdell, Carol
AU - Boat, Thomas F.
AU - Clark, Noreen
AU - Drotar, Dennis
AU - Lewin, Daniel
AU - Marshall, Bruce C.
AU - Punturieri, Antonello
AU - Redline, Susan
AU - Reed, Shelby D.
AU - Schatz, Michael
AU - Smith, Robert
AU - Soumerai, Stephen B.
AU - Thompson, B. Taylor
PY - 2011/10/1
Y1 - 2011/10/1
N2 - The Division of Lung Diseases of the National Heart, Lung, and Blood Institute (NHLBI) held a workshop to develop recommendations on topics, methodologies, and resources for comparative effectiveness research (CER) that will guide clinical decision making about available treatment options for lung diseases and sleep disorders. A multidisciplinary group of experts with experience in efficacy, effectiveness, implementation, andeconomic research identified (a) what types of studies the domain of CER in lung diseases and sleep disorders should include, (b) the criteria and process for setting priorities, and (c) current resources for and barriers to CER in lung diseases. Key recommendations were to (1) increase efforts to engage stakeholders in developing CER questions and study designs; (2) invest in further development of databases and other infrastructure, including efficient methods for data sharing; (3) make full use of a broad range of study designs; (4) increase the appropriate use of observational designs and the support of methodologic research; (5) ensure that committees that review CER grant applications include persons with appropriate perspective and expertise; and (6) further develop the workforce for CER by supporting training opportunities that focus on the methodologic and practical skills needed.
AB - The Division of Lung Diseases of the National Heart, Lung, and Blood Institute (NHLBI) held a workshop to develop recommendations on topics, methodologies, and resources for comparative effectiveness research (CER) that will guide clinical decision making about available treatment options for lung diseases and sleep disorders. A multidisciplinary group of experts with experience in efficacy, effectiveness, implementation, andeconomic research identified (a) what types of studies the domain of CER in lung diseases and sleep disorders should include, (b) the criteria and process for setting priorities, and (c) current resources for and barriers to CER in lung diseases. Key recommendations were to (1) increase efforts to engage stakeholders in developing CER questions and study designs; (2) invest in further development of databases and other infrastructure, including efficient methods for data sharing; (3) make full use of a broad range of study designs; (4) increase the appropriate use of observational designs and the support of methodologic research; (5) ensure that committees that review CER grant applications include persons with appropriate perspective and expertise; and (6) further develop the workforce for CER by supporting training opportunities that focus on the methodologic and practical skills needed.
KW - Implementation
KW - Methodology
KW - Observational studies
KW - Randomized controlled trials
KW - Study designs
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U2 - 10.1164/rccm.201104-0634WS
DO - 10.1164/rccm.201104-0634WS
M3 - Article
C2 - 21965016
AN - SCOPUS:80053429310
SN - 1073-449X
VL - 184
SP - 848
EP - 856
JO - American journal of respiratory and critical care medicine
JF - American journal of respiratory and critical care medicine
IS - 7
ER -