Abstract
A DNA-library established from microdissected bands 8q23 to 8q24.1 of normal human chromosomes 8 (Lüdecke et al., 1989) was used as a probe for chromosomal in situ suppression (CISS-) hybridization to metaphase chromosomes of man and primates including Hylobates lar and Macaca fuscata. Comparative band mapping as first applied in this study shows the specific visualization of a single subchromosomal region in all three species and thus demonstrates that synteny of the bulk sequences of a specific human chromosome subregion has been conserved for more than 20 million years.
Original language | English (US) |
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Pages (from-to) | 67-71 |
Number of pages | 5 |
Journal | Human Evolution |
Volume | 6 |
Issue number | 1 |
DOIs | |
State | Published - Feb 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Ecology, Evolution, Behavior and Systematics