Comment on “sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”

Abdel Aouacheria; Kyle W. Cunningham; J. Marie Hardwick; Zdena Palkova; Ted Powers; Fedor F. Severin; Libuše Váchova

doi:10.1126/science.aar6910

Comment on “sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”

Abdel Aouacheria, Kyle W. Cunningham, J. Marie Hardwick, Zdena Palkova, Ted Powers, Fedor F. Severin, Libuše Váchova

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.

Original language	English (US)
Article number	eaar6910
Journal	Science
Volume	360
Issue number	6395
DOIs	https://doi.org/10.1126/science.aar6910
State	Published - Jun 22 2018

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title = "Comment on “sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”",

abstract = "Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.",

author = "Abdel Aouacheria and Cunningham, {Kyle W.} and Hardwick, {J. Marie} and Zdena Palkova and Ted Powers and Severin, {Fedor F.} and Libu{\v s}e V{\'a}chova",

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AU - Aouacheria, Abdel

AU - Cunningham, Kyle W.

AU - Hardwick, J. Marie

AU - Palkova, Zdena

AU - Powers, Ted

AU - Severin, Fedor F.

AU - Váchova, Libuše

PY - 2018/6/22

Y1 - 2018/6/22

N2 - Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.

AB - Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.

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JF - Science

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Comment on “sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”

Abstract

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