Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme"

Feng Wang, Anand Ranjan, Debbie Wei, Carl Wu

Research output: Contribution to journalReview articlepeer-review

Abstract

Watanabe et al. (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange.

Original languageEnglish (US)
Pages (from-to)358a
JournalScience
Volume353
Issue number6297
DOIs
StatePublished - Jul 22 2016
Externally publishedYes

ASJC Scopus subject areas

  • General

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