Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme"

Feng Wang; Anand Ranjan; Debbie Wei; Carl Wu

doi:10.1126/science.aad5921

Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme"

Feng Wang, Anand Ranjan, Debbie Wei, Carl Wu

Research output: Contribution to journal › Review article › peer-review

Abstract

Watanabe et al. (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange.

Original language	English (US)
Pages (from-to)	358a
Journal	Science
Volume	353
Issue number	6297
DOIs	https://doi.org/10.1126/science.aad5921
State	Published - Jul 22 2016
Externally published	Yes

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title = "Comment on {"}A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme{"}",

abstract = "Watanabe et al. (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange.",

author = "Feng Wang and Anand Ranjan and Debbie Wei and Carl Wu",

note = "Publisher Copyright: Copyright {\textcopyright} 2016 by the American Association for the Advancement of Science.",

year = "2016",

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AU - Wang, Feng

AU - Ranjan, Anand

AU - Wei, Debbie

AU - Wu, Carl

PY - 2016/7/22

Y1 - 2016/7/22

N2 - Watanabe et al. (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange.

AB - Watanabe et al. (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange.

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JO - Science

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Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme"

Abstract

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