Abstract
Purpose: To evaluate the combined use of carbon dioxide (CO2) and a gadolinium-based blood-pool agent for magnetic resonance angiography (MRA). Materials and Methods: After an initial intravenous injection of the blood-pool agent Gadomer (Schering AG, Germany), repeated transcatheter CO 2 injections were performed in the aorta and the renal arteries of two fully-anesthetized pigs. Real-time images were acquired using a true fast imaging with steady-state precession (FISP) sequence. Results: During the CO2 injections, the Gadomer-enhanced blood was totally replaced, resulting in an immediate, temporary, total signal loss in the vessel lumen. Susceptibility artifacts during the injections or catheter manipulations rarely occurred. Conclusion: Due to T1-shortening, the circulating blood-pool agent prevents flow artifacts during catheter manipulations because the steady-state is reached much earlier. Therefore, this double-contrast MRA method improves catheter conspicuity and might be helpful for guiding and controlling intravascular procedures during interventional MRI.
Original language | English (US) |
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Pages (from-to) | 645-649 |
Number of pages | 5 |
Journal | Journal of Magnetic Resonance Imaging |
Volume | 21 |
Issue number | 5 |
DOIs | |
State | Published - May 2005 |
Keywords
- Artifact reduction
- Blood pool agent
- Carbon dioxide
- Interventional MRI
- MRA
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging