COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINE-DICHLORO-PLATINUM, VINBLASTINE, AND BLEOMYCIN IN ADVANCED TESTICULAR NON-SEMINOMA

G. Stoter; D. Th Sleijfer; C. P J Vendrik; H. Schraffordt Koops; A. Struyvenberg; A. T Van Oosterom; Th M. Brouwers; H. M. Pinedo

doi:10.1016/S0140-6736(79)91719-7

COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINE-DICHLORO-PLATINUM, VINBLASTINE, AND BLEOMYCIN IN ADVANCED TESTICULAR NON-SEMINOMA

G. Stoter
, D. Th Sleijfer
, C. P J Vendrik
, H. Schraffordt Koops
, A. Struyvenberg
, A. T Van Oosterom
, Th M. Brouwers
, H. M. Pinedo

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. Complete remission was achieved in 24 (60%) patients and partial remission in 11(28%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5-30 months. There were 3 drug-related deaths. This regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. Patients should be treated in centres experienced in the specialised management of this potentially curable disease.

Original language	English (US)
Pages (from-to)	941-945
Number of pages	5
Journal	The Lancet
Volume	313
Issue number	8123
DOIs	https://doi.org/10.1016/S0140-6736(79)91719-7
State	Published - May 5 1979
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1016/S0140-6736(79)91719-7

Cite this

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title = "COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINE-DICHLORO-PLATINUM, VINBLASTINE, AND BLEOMYCIN IN ADVANCED TESTICULAR NON-SEMINOMA",

abstract = "40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. Complete remission was achieved in 24 (60\%) patients and partial remission in 11(28\%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5-30 months. There were 3 drug-related deaths. This regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. Patients should be treated in centres experienced in the specialised management of this potentially curable disease.",

author = "G. Stoter and Sleijfer, \{D. Th\} and Vendrik, \{C. P J\} and Koops, \{H. Schraffordt\} and A. Struyvenberg and Oosterom, \{A. T Van\} and Brouwers, \{Th M.\} and Pinedo, \{H. M.\}",

year = "1979",

month = may,

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doi = "10.1016/S0140-6736(79)91719-7",

language = "English (US)",

volume = "313",

pages = "941--945",

journal = "The Lancet",

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TY - JOUR

T1 - COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINE-DICHLORO-PLATINUM, VINBLASTINE, AND BLEOMYCIN IN ADVANCED TESTICULAR NON-SEMINOMA

AU - Stoter, G.

AU - Sleijfer, D. Th

AU - Vendrik, C. P J

AU - Koops, H. Schraffordt

AU - Struyvenberg, A.

AU - Oosterom, A. T Van

AU - Brouwers, Th M.

AU - Pinedo, H. M.

PY - 1979/5/5

Y1 - 1979/5/5

N2 - 40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. Complete remission was achieved in 24 (60%) patients and partial remission in 11(28%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5-30 months. There were 3 drug-related deaths. This regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. Patients should be treated in centres experienced in the specialised management of this potentially curable disease.

AB - 40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. Complete remission was achieved in 24 (60%) patients and partial remission in 11(28%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5-30 months. There were 3 drug-related deaths. This regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. Patients should be treated in centres experienced in the specialised management of this potentially curable disease.

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UR - https://www.scopus.com/pages/publications/0018746157#tab=citedBy

U2 - 10.1016/S0140-6736(79)91719-7

DO - 10.1016/S0140-6736(79)91719-7

M3 - Article

C2 - 87614

AN - SCOPUS:0018746157

SN - 0140-6736

VL - 313

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EP - 945

JO - The Lancet

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IS - 8123

ER -

COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINE-DICHLORO-PLATINUM, VINBLASTINE, AND BLEOMYCIN IN ADVANCED TESTICULAR NON-SEMINOMA

Abstract

ASJC Scopus subject areas

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