Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis

Abhishek Gami; John Woller; Paul Scheel; Syed Abbas Ali; Carol Ann Huff; Charles Steenbergen; Marc Halushka; Kavita Sharma; Michael Polydefkis; Joban Vaishnav

doi:10.1016/j.jaccas.2024.102285

Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis

Abhishek Gami, John Woller, Paul Scheel, Syed Abbas Ali, Carol Ann Huff, Charles Steenbergen, Marc Halushka, Kavita Sharma, Michael Polydefkis, Joban Vaishnav

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur. We present three cases of coexisting AL and ATTR cardiac amyloidosis and demonstrate the importance of clinical history and endomyocardial biopsy in diagnosis of this rare entity.

Original language	English (US)
Article number	102285
Journal	JACC: Case Reports
Volume	29
Issue number	7
DOIs	https://doi.org/10.1016/j.jaccas.2024.102285
State	Published - Apr 3 2024

Keywords

cardiac amyloidosis
endomyocardial biopsy
light chain
transthyretin

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jaccas.2024.102285

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title = "Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis",

abstract = "Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur. We present three cases of coexisting AL and ATTR cardiac amyloidosis and demonstrate the importance of clinical history and endomyocardial biopsy in diagnosis of this rare entity.",

keywords = "cardiac amyloidosis, endomyocardial biopsy, light chain, transthyretin",

author = "Abhishek Gami and John Woller and Paul Scheel and Ali, {Syed Abbas} and Huff, {Carol Ann} and Charles Steenbergen and Marc Halushka and Kavita Sharma and Michael Polydefkis and Joban Vaishnav",

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doi = "10.1016/j.jaccas.2024.102285",

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AU - Gami, Abhishek

AU - Woller, John

AU - Scheel, Paul

AU - Ali, Syed Abbas

AU - Huff, Carol Ann

AU - Steenbergen, Charles

AU - Halushka, Marc

AU - Sharma, Kavita

AU - Polydefkis, Michael

AU - Vaishnav, Joban

PY - 2024/4/3

Y1 - 2024/4/3

N2 - Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur. We present three cases of coexisting AL and ATTR cardiac amyloidosis and demonstrate the importance of clinical history and endomyocardial biopsy in diagnosis of this rare entity.

AB - Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur. We present three cases of coexisting AL and ATTR cardiac amyloidosis and demonstrate the importance of clinical history and endomyocardial biopsy in diagnosis of this rare entity.

KW - cardiac amyloidosis

KW - endomyocardial biopsy

KW - light chain

KW - transthyretin

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ER -

Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

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