Cocaine-mediated enhancement of Tat toxicity in rat hippocampal cell cultures: The role of oxidative stress and D1 dopamine receptor

Chemical Compounds

• Oxidative Stress 78%
• Neurotoxicity 74%
• Dopamine 74%
• Cocaine 71%
• Neurotoxic 50%
• Trolox 50%
• Reactive Oxygen Metabolite 37%
• Dopamine 1 Receptor Blocking Agent 36%
• SCH 23390 32%
• Protein 32%
• Dose 30%
• Antioxidant Agent 30%
• Psychotropic Agent 27%
• Vitamin E 23%
• Depolarization 22%
• Non Toxic 20%
• Cell Viability 19%
• Toxic 14%
• Oxidation Reaction 8%

Medicine & Life Sciences

• Dopamine D1 Receptors 100%
• Cocaine 79%
• Cell Culture Techniques 60%
• Oxidative Stress 58%
• 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 44%
• HIV-1 41%
• Reactive Oxygen Species 25%
• Antioxidants 23%
• AIDS Dementia Complex 22%
• tat Gene Products 22%
• Viral Envelope Proteins 22%
• Human Immunodeficiency Virus Proteins 21%
• SCH 23390 20%
• Dopamine Antagonists 19%
• Psychotropic Drugs 18%
• Vitamin E 16%
• Cell Survival 12%
• Poisons 11%
• HIV 10%
• Aptitude 10%
• Water 10%
• Neurons 9%
• Brain 7%
• Proteins 5%