Cocaine colitis - Is this a new syndrome?

Rhonda Fishel, Gary Hamamoto, Adrian Barbul, Violet Jiji, Gershon Efron

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


An unusual case of colitis in a 37-year-old cocaine addict is described. The patient presented with right-sided abdominal pain and diarrhea exacerbated by his use of cocaine. Significant antibiotic ingestion was denied. At laparotomy, an edematous cecum and ascending colon were found, the cut surface of which revealed diffuse superficial ulcerations and yellowish fibrinous material. Microscopic examination demonstrated findings consistent with pseudomembranous colitis with an ischemic component. A mechanism involving chathecholamine-induced mucosal ischemia is postulated to explain the findings seen in this patient.

Original languageEnglish (US)
Pages (from-to)264-266
Number of pages3
JournalDiseases of the Colon & Rectum
Issue number4
StatePublished - Apr 1 1985


  • Catecholamines
  • Cocaine
  • Diarrhea
  • Ischemic colitis
  • Pseudomembranous colitis

ASJC Scopus subject areas

  • Gastroenterology


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