CNS Lesions in Neonatal Isoimmune Thrombocytopenia

Sakkubai Naidu, Harry Messmore, Vito Caserta, Michael Fine

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


We treated two siblings with classic neonatal isoimmune thrombocytopenia and porencephalic cysts in whom the CNS lesions occurred in a vascular distribution, for which there is no clear explanation. Whether the CNS vasculature is injured by the immune process at certain susceptible sites in larger vessels or whether there is a thrombotic process occurring at sites of vascular injury is speculative. This observation suggests that vascular factors are involved in the development of CNS lesions in this condition.

Original languageEnglish (US)
Pages (from-to)552-554
Number of pages3
JournalArchives of neurology
Issue number9
StatePublished - Sep 1983
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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