CMAP: Complement map database

Kun Yang; Ashok R. Dinasarapu; Edimara S. Reis; Robert A. Deangelis; Daniel Ricklin; Shankar Subramaniam; John D. Lambris

doi:10.1093/bioinformatics/btt269

CMAP: Complement map database

Kun Yang, Ashok R. Dinasarapu, Edimara S. Reis, Robert A. Deangelis, Daniel Ricklin, Shankar Subramaniam, John D. Lambris

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in health and disease and extensively communicates with associated physiological pathways ranging from immunity and inflammation to homeostasis and development. A steady stream of experimental data reveals new fascinating connections at a rapid pace; although opening unique opportunities for research discoveries, the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sources renders it highly challenging to keep up with the essential findings. With the Complement Map Database (CMAP), we have created a novel and easily accessible research tool to assist the complement community and scientists from related disciplines in exploring the complement network and discovering new connections.

Original language	English (US)
Pages (from-to)	1832-1833
Number of pages	2
Journal	Bioinformatics
Volume	29
Issue number	14
DOIs	https://doi.org/10.1093/bioinformatics/btt269
State	Published - Jul 15 2013
Externally published	Yes

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

Access to Document

10.1093/bioinformatics/btt269

Cite this

@article{792604d83f4547dfaf1d5de253cee00d,

title = "CMAP: Complement map database",

abstract = "The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in health and disease and extensively communicates with associated physiological pathways ranging from immunity and inflammation to homeostasis and development. A steady stream of experimental data reveals new fascinating connections at a rapid pace; although opening unique opportunities for research discoveries, the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sources renders it highly challenging to keep up with the essential findings. With the Complement Map Database (CMAP), we have created a novel and easily accessible research tool to assist the complement community and scientists from related disciplines in exploring the complement network and discovering new connections.",

author = "Kun Yang and Dinasarapu, {Ashok R.} and Reis, {Edimara S.} and Deangelis, {Robert A.} and Daniel Ricklin and Shankar Subramaniam and Lambris, {John D.}",

year = "2013",

month = jul,

day = "15",

doi = "10.1093/bioinformatics/btt269",

language = "English (US)",

volume = "29",

pages = "1832--1833",

journal = "Bioinformatics",

issn = "1367-4803",

publisher = "Oxford University Press",

number = "14",

}

TY - JOUR

T1 - CMAP

T2 - Complement map database

AU - Yang, Kun

AU - Dinasarapu, Ashok R.

AU - Reis, Edimara S.

AU - Deangelis, Robert A.

AU - Ricklin, Daniel

AU - Subramaniam, Shankar

AU - Lambris, John D.

PY - 2013/7/15

Y1 - 2013/7/15

N2 - The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in health and disease and extensively communicates with associated physiological pathways ranging from immunity and inflammation to homeostasis and development. A steady stream of experimental data reveals new fascinating connections at a rapid pace; although opening unique opportunities for research discoveries, the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sources renders it highly challenging to keep up with the essential findings. With the Complement Map Database (CMAP), we have created a novel and easily accessible research tool to assist the complement community and scientists from related disciplines in exploring the complement network and discovering new connections.

AB - The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in health and disease and extensively communicates with associated physiological pathways ranging from immunity and inflammation to homeostasis and development. A steady stream of experimental data reveals new fascinating connections at a rapid pace; although opening unique opportunities for research discoveries, the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sources renders it highly challenging to keep up with the essential findings. With the Complement Map Database (CMAP), we have created a novel and easily accessible research tool to assist the complement community and scientists from related disciplines in exploring the complement network and discovering new connections.

UR - http://www.scopus.com/inward/record.url?scp=84880227062&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880227062&partnerID=8YFLogxK

U2 - 10.1093/bioinformatics/btt269

DO - 10.1093/bioinformatics/btt269

M3 - Article

C2 - 23661693

AN - SCOPUS:84880227062

SN - 1367-4803

VL - 29

SP - 1832

EP - 1833

JO - Bioinformatics

JF - Bioinformatics

IS - 14

ER -

CMAP: Complement map database

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this