Cloud-scale RNA-sequencing differential expression analysis with Myrna.

Research output: Contribution to journalArticlepeer-review

231 Scopus citations


As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from

Original languageEnglish (US)
Pages (from-to)R83
JournalGenome biology
Issue number8
StatePublished - 2010

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology


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