Closing the gap: Unmet needs of individuals with impulsive aggressive behavior observed in children and adolescents

Adelaide S. Robb, Daniel F. Connor, Birgit H. Amann, Benedetto Vitiello, Azmi Nasser, Welton O'Neal, Stefan Schwabe, Gianpiera Ceresoli-Borroni, Jeffrey H. Newcorn, Shawn A. Candler, Jan K. Buitelaar, Robert L. Findling

Research output: Contribution to journalReview articlepeer-review


Impulsive aggressive (IA, or impulsive aggression) behavior describes an aggregate set of maladaptive, aggressive behaviors occurring across multiple neuropsychiatric disorders. IA is reactive, eruptive, sudden, and unplanned; it provides information about the severity, but not the nature, of its associated primary disorder. IA in children and adolescents is of serious clinical concern for patients, families, and physicians, given the detrimental impact pediatric IA can have on development. Currently, the ability to properly identify, monitor, and treat IA behavior across clinical populations is hindered by two major roadblocks: (1) the lack of an assessment tool designed for and sensitive to the set of behaviors comprising IA, and (2) the absence of a treatment indicated for IA symptomatology. In this review, we discuss the clinical gaps in the approach to monitoring and treating IA behavior, and highlight emerging solutions that may improve clinical outcomes in patients with IA.

Original languageEnglish (US)
Pages (from-to)448-456
Number of pages9
JournalCNS spectrums
Issue number5
StatePublished - Oct 31 2021
Externally publishedYes


  • Key words ADHD
  • assessment tool
  • impulsive aggression
  • maladaptive aggression
  • unmet needs

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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