Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

M. E. Smith; L. A. Stone; P. S. Albert; J. A. Frank; R. Martin; M. Armstrong; H. Maloni; D. E. McFarlin; H. F. McFarland

Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

M. E. Smith, L. A. Stone, P. S. Albert, J. A. Frank, R. Martin, M. Armstrong, H. Maloni, D. E. McFarlin, H. F. McFarland

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244 Scopus citations

Abstract

It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

Original language	English (US)
Pages (from-to)	480-489
Number of pages	10
Journal	Annals of Neurology
Volume	33
Issue number	5
State	Published - May 1993
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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title = "Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions",

abstract = "It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS] ",

author = "Smith, {M. E.} and Stone, {L. A.} and Albert, {P. S.} and Frank, {J. A.} and R. Martin and M. Armstrong and H. Maloni and McFarlin, {D. E.} and McFarland, {H. F.}",

year = "1993",

month = may,

language = "English (US)",

volume = "33",

pages = "480--489",

journal = "Annals of Neurology",

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T1 - Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

AU - Smith, M. E.

AU - Stone, L. A.

AU - Albert, P. S.

AU - Frank, J. A.

AU - Martin, R.

AU - Armstrong, M.

AU - Maloni, H.

AU - McFarlin, D. E.

AU - McFarland, H. F.

PY - 1993/5

Y1 - 1993/5

N2 - It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

AB - It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

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SN - 0364-5134

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JO - Annals of Neurology

JF - Annals of Neurology

IS - 5

ER -

Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

Abstract

ASJC Scopus subject areas

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