Clinical trials with canine distemper vaccines in exotic carnivores.

R. J. Montali, C. R. Bartz, J. A. Teare, J. T. Allen, M. J. Appel, M. Bush

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


Two types of killed canine distemper virus (CDV) vaccine and a modified-live CDV vaccine were clinically evaluated in four species of exotic carnivores. In 16 trials in which 13 red pandas (Ailurus fulgens) were given the killed vaccine, only 1 animal had a virus-neutralization titer that exceeded 1:100. A red panda given modified-live CDV vaccine deemed safe for gray foxes and ferrets died of bacterial pneumonia 16 days later. There was no pathologic evidence of canine distemper in that panda. The same modified-live vaccine proved to be immunogenic and safe in 12 bush dogs (Speothos venaticus), 5 maned wolves (Chrysocyon brachyurus), and 3 fennec foxes (Fennecus zerda) in which virus-neutralization titers often exceeded 1:512 and persisted for several months after vaccination.

Original languageEnglish (US)
Pages (from-to)1163-1167
Number of pages5
JournalJournal of the American Veterinary Medical Association
Issue number11
StatePublished - Dec 1 1983

ASJC Scopus subject areas

  • General Veterinary


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