Clinical trials in gynecological cancer

E. L. Trimble, J. Davis, P. Disaia, K. Fujiwara, D. Gaffney, G. Kristensen, J. Ledermann, J. Pfisterer, M. Quinn, N. Reed, M. Schoenfeldt, J. T. Thigpen

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


The Gynecologic Cancer Intergroup is comprised representatives from international gynecological cancer trials organizations, which collaborate in multicenter studies to answer the clinical challenges in gynecological cancer. This review article highlights the key clinical questions facing clinical trialists over the next decade, the information and infrastructure resources available for trials, and the methods of trial development. We cover human papillomavirus (HPV)-associated neoplasia, including cervical cancer, together with endometrial cancer, ovarian cancer, and vulvar cancer. Infrastructure for clinical trials includes a database for trials, templates for protocol development, patient educational material, and financial support for clinical trials. Other critical issues include support from government and charities and government regulations.

Original languageEnglish (US)
Pages (from-to)547-556
Number of pages10
JournalInternational Journal of Gynecological Cancer
Issue number3
StatePublished - May 1 2007
Externally publishedYes


  • Cervical cancer
  • Clinical trials
  • Endometrial cancer
  • GCIG
  • Gynecologic cancer
  • Ovarian cancer

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


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