Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome

Pieter C. Stuiver, John L. Ziegler, John B. Wood, Richard H. Morrow, M. S.R. Hutt

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A controlled, randomized, double-blind trial of malaria prophylaxis in tropical splenomegaly syndrome showed a significant reduction in spleen size and an improvement of anaemia and symptoms in patients treated with antimalarials compared with control subjects receiving placebo. This study confirms the observations from West Africa and provides further indirect evidence for a malarial aetiology of tropical splenomegaly syndrome.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalBritish medical journal
Issue number5746
StatePublished - Feb 20 1971
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome'. Together they form a unique fingerprint.

Cite this