Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome

Pieter C. Stuiver; John L. Ziegler; John B. Wood; Richard H. Morrow; M. S.R. Hutt

doi:10.1136/bmj.1.5746.426

Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome

Pieter C. Stuiver, John L. Ziegler, John B. Wood, Richard H. Morrow, M. S.R. Hutt

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Abstract

A controlled, randomized, double-blind trial of malaria prophylaxis in tropical splenomegaly syndrome showed a significant reduction in spleen size and an improvement of anaemia and symptoms in patients treated with antimalarials compared with control subjects receiving placebo. This study confirms the observations from West Africa and provides further indirect evidence for a malarial aetiology of tropical splenomegaly syndrome.

Original language	English (US)
Pages (from-to)	426-429
Number of pages	4
Journal	British medical journal
Volume	1
Issue number	5746
DOIs	https://doi.org/10.1136/bmj.1.5746.426
State	Published - Feb 20 1971
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome

Abstract

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