Abstract
We have noted that values for serum creatine phosphokinase (CPK) are frequently low in patients with connective tissue diseases. Geometric mean values were 96.0 units/L among 121 disease-free males and 50.2 units/L among 63 disease-free females. The geometric mean values were 31.7 units/L in 11 males and 35.2 units/L in 49 females with systemic lupus erythematosus; 15.1 units/L in three males and 13.0 units/L in ten females with rheumatoid arthritis; and 41.6 units/L in 19 females with Sjögren's syndrome. Values within the normal range may occur in the face of active myositis in these illnesses. Findings of a low serum CPK value may occur in the absence of steroid treatment. Thus, a low serum CPK value is frequently found in patients with connective tissue diseases and a normal value should not dissuade one from the diagnosis of myositis. (JAMA 1981;246:1921-1923).
Original language | English (US) |
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Pages (from-to) | 1921-1923 |
Number of pages | 3 |
Journal | Journal of the American Medical Association |
Volume | 246 |
Issue number | 17 |
DOIs | |
State | Published - Oct 23 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)