Abstract
The clinical performance of the Aptima® HIV-1 Quant Dx, Aptima HCV Quant Dx, and Aptima HBV Quant Dx were evaluated and compared to the Roche cobas HIV-1, HCV, and HBV assays performed on the Roche cobas 6800 system. The Aptima Quant assays exhibited an overall percent agreement of 99.4% for HBV, 98.3% for HCV, and 85.14% for HIV-1. The average log difference between the Aptima and Roche assays was below 0.2 IU (or copies)/mL and the quantitative correlation's (R-squared value (R2)) was between 0.95 and 0.97. The Aptima viral assays demonstrated a high level of quantitative correlation with the Roche cobas assays for HCV, HBV, and HIV-1.
Original language | English (US) |
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Article number | 115951 |
Journal | Diagnostic Microbiology and Infectious Disease |
Volume | 106 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2023 |
Keywords
- Aptima
- HIV-1, HCV, HBV
- cobas
- viral load
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases