Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center

Amanda Rey, Victor Llorenç, Laura Pelegrín, Marina Mesquida, Blanca Molins, José Rios, Jose Fernando Arévalo, Alfredo Adán

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background/Aims: To analyze the clinical pattern of ocular toxoplasmosis in a referral center in Spain. Methods: The medical records of consecutive patients with ocular toxoplasmosis admitted from a single referral center for uveitis in Barcelona (Spain) were retrospectively analyzed between January 2005 and January 2011. Results: One hundred and thirteen eyes from 113 patients (74 Spanish and 39 South American) with active ocular toxoplasmosis were analyzed with a 12-month follow-up. Final BCVA ≤20/200 was found in 30 eyes (26.5%). The most frequent complications were macular edema (16.8%) and epiretinal membrane (11.5%). Anterior chamber cell scores of ≥2+ (p = 0.003), vitreous cell scores of ≥2+ (p = 0.001), and the presence of cataracts (p = 0.047) or serous retinal detachment (p = 0.008) were more common among the South American than Spanish cohort. Active macular lesions (p < 0.001) with an initial BCVA ≤20/200 (p < 0.001) and advanced age (p = 0.019) were predictors for final BCVA ≤20/200, whereas female gender (p = 0.021) and an initial BCVA ≤20/200 (p = 0.045) were predictors for ocular complications. Moreover, a BCVA ≤20/200 (p < 0.001) and a vitreous cell score of ≥2+ (p = 0.045) at the initial examination were predictors of an eventual need for ocular surgery. Conclusion: The clinical features of ocular toxoplasmosis in Spanish patients differ from those of South American patients. In general, active macular lesions with an initial BCVA ≤20/200 and advanced age were shown to be predictors for final BCVA ≤20/200 in our patient cohort.

Original languageEnglish (US)
Pages (from-to)173-178
Number of pages6
Issue number3
StatePublished - Apr 2013


  • Ocular toxoplasmosis
  • Retinochoroiditis
  • Toxoplasma gondii
  • Uveitis

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


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